3-rx.comCustomer Support
3-rx.com
   
HomeAbout UsFAQContactHelp
News Center
Health Centers
Medical Encyclopedia
Drugs & Medications
Diseases & Conditions
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
Diet & Nutrition
Special Topics



Depression is a medical condition that leads to intense feelings of sadness or despair. These feelings don't go away on their own. They are not necessarily related to a particular life event


Join our Mailing List





Syndicate

You are here : 3-RX.com > Home > AIDS/HIV - Infections -

New research examines how HIV infections occur on the molecular level

AIDS/HIV • • InfectionsJan 19, 11

The UK’s National Physical Laboratory (NPL) with the University of Edinburgh and IBM’s TJ Watson Research Center have published new research about the structure of an HIV-1 protein that could help to develop new drugs to stop the virus infecting healthy cells.

The research provides a new insight into how the changes in structure of a small part of an HIV protein (a membrane proximal peptide) may alter the infection of the virus into healthy cells. The team was able to observe key changes in this part of the protein implicated in the early stages of the infection by using a combination of powerful experimental and computational tools. This is the first attempt to demonstrate that the inducible binding of the peptide with membrane-like surfaces can serve as a responsive molecular anchor underpinning HIV fusion to target cells.

This information is important as it gives us a better understanding of how HIV infections take hold at the molecular level. Drug designers could use this information to develop treatments that stop HIV from entering a healthy cell and infecting it.

This research is a part of the NPL-led international research project ‘Multiscale measurements in biophysical systems’, which is jointly funded by NPL and the Scottish Universities Physics Alliance.

The team’s journal article detailing this research was selected as the featured article in the January 2011 issue of the journal Physical Chemistry Chemical Physics – the Royal Society of Chemistry’s premier forum for physical chemistry research.

###

Contact: Joe Meaney
.(JavaScript must be enabled to view this email address)
44-845-680-1864
National Physical Laboratory



Print Version
Tell-a-Friend
comments powered by Disqus

RELATED ARTICLES:
  Vinegar kills tuberculosis and other mycobacteria
  New strategy emerges for fighting drug-resistant malaria
  Toys, books, cribs harbor bacteria for long periods, study finds
  California high school to test students for tuberculosis
  TB Vaccine May Work Against Multiple Sclerosis
  HIV-1 movement across genital tract cells surprisingly enhanced by usurping antibody response
  Tuberculosis: Nature has a double-duty antibiotic up her sleeve
  Treatment target identified for a public health risk parasite
  Nearly half of U.S. children late receiving vaccines
  MMV develops framework to assess risk of resistance for antimalarial compounds
  Father of Ga. woman with flesh-eating disease says she’s suffering worst pain of entire ordeal
  Georgia woman with flesh-eating disease in “critical” condition

 












Home | About Us | FAQ | Contact | Advertising Policy | Privacy Policy | Bookmark Site