3-rx.comCustomer Support
HomeAbout UsFAQContactHelp
News Center
Health Centers
Medical Encyclopedia
Drugs & Medications
Diseases & Conditions
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
Diet & Nutrition
Special Topics

\"$alt_text\"');"); } else { echo"\"$alt_text\""; } ?>

Join our Mailing List


You are here : 3-RX.com > Home > Heart -

Statins before carotid surgery may be beneficial

HeartOct 15, 05

Patients with symptoms of low blood flow to the brain who take statins before undergoing carotid endarterectomy, a type of surgery that may help prevent strokes, may fare better early after the surgery than those who do not, Canadian researchers have found.

The carotid arteries, which lie on each side of the neck, are the major vessels that supply blood to the brain. Strokes can occur when plaques that have formed in the carotids break off or otherwise obstruct blood flow to the brain. Carotid endarterectomy involves making a small incision in the affected artery and inserting an instrument to remove the plaque.

The current study shows that those taking statins are “less likely to die or have a stroke due to the operation,” said study chief Dr. James Kennedy. Why this is so is not exactly clear and requires further study. Nonetheless, the current study suggests that individuals having vascular surgery “may benefit from being on a statin prior to surgery,” he said.

Kennedy of the University of Alberta, Edmonton, and colleagues note that statin use has been associated with a reduction in mortality in non-cardiac surgery and they sought to determine whether this might also be true in patients admitted for carotid endarterectomy.

The researchers reviewed the records of more than 3000 patients who underwent the procedure during a 2-year period. Overall, 815 of 2031 patients with symptoms of low blood flow to the brain (i.e., the symptomatic patients) and 665 of 1252 symptom-free patients were taking a statin at the time of hospital admission.

Neither group showed an improvement in in-hospital cardiac outcomes, but statin use by symptomatic patients was associated with a reduced risk of experiencing a stroke while still in the hospital or of dying in the hospital. No benefit was seen in the patients who did not have symptoms prior to the surgery.

Despite the apparent beneficial effects of statins in symptomatic patients, the researchers note the study was observational and the ostensible advantage “now needs to be explored in rigorously performed randomized controlled trials.”

In an accompanying editorial, Dr. David M. Kent of Tufts-New England Medical Center, Boston, notes that given the size of the study “the results cannot be dismissed lightly,” but agrees with the need for rigorous testing.

SOURCE: Stroke, October 2005.

Print Version
comments powered by Disqus

  New superfoods could help key protein keep bodies healthy
  Mobile app on emergency cardiac care aids best decisions in seconds
  Train your heart to protect your mind
  Mass. General study identifies path to safer drugs for heart disease, cancer
  Tweaking MRI to track creatine may spot heart problems earlier, Penn Medicine study suggests
  Method to estimate LDL-C may provide more accurate risk classification
  Texting heart medication reminders improved patient adherence
  Hybrid heart valve is strong, durable in early tests
  Cardiopoietic ‘Smart’ Stem Cells Show Promise in Heart Failure Patients
  Vitamin D deficiency ups heart disease risk
  Heart surgery safe in Jehovah’s Witnesses
  Magnet helps target transplanted iron-loaded cells to key areas of heart


Home | About Us | FAQ | Contact | Advertising Policy | Privacy Policy | Bookmark Site