3-rx.comCustomer Support
HomeAbout UsFAQContactHelp
News Center
Health Centers
Medical Encyclopedia
Drugs & Medications
Diseases & Conditions
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
Diet & Nutrition
Special Topics

\"$alt_text\"');"); } else { echo"\"$alt_text\""; } ?>

Join our Mailing List


You are here : 3-RX.com > Home > Trauma -

Stem cells aid spinal cord injured

TraumaSep 19, 05

Human neural stem cells can replace damaged cells and improve function in a mouse model of spinal cord injury, according to a report released Monday.

For treating spinal cord injury, “there is hope, but we are a long way off,” said Dr. Brian J. Cummings from University of California, Irvine. “Our study improved function in mice with very controlled injuries. We did not cure these mice.”

Cummings and colleagues injected human neural stem cells into the site of spinal cord contusion injury in mice and followed their progress.

The human cells survived and engrafted extensively within the injured mouse spinal cord, the authors report, with cells persisting 17 weeks after transplantation.

Injected neural stem cells differentiated into neurons and formed synapses—connections between neurons, the researchers note.

Mice injected with human neural stem cells showed evidence of recovering coordinated locomotor function and stepping ability 16 weeks after engraftment, the report indicates.

“To our knowledge,” the investigators write, “this is the longest time that mice receiving stem cell grafts of any type have been tracked behaviorally.”

Treatment of mice with toxin targeting the human cells resulted in decreased locomotor function, the results indicate. “This suggests that at least some of the recovery was the result of integration between the grafted cells and the host cells,” Cummings said.

Summing up, Cummings said future treatments for spinal cord injury will likely involve a combination of therapies noting that “spinal cord injury is a very complex syndrome, and no one treatment will solve the entire problem.”

SOURCE: PNAS Early Online Edition, September 19, 2005.

Print Version
comments powered by Disqus

  Dislocating a hip after total hip replacement can be a traumatic experience
  Study suggests increase in falls among the elderly
  Study finds axon regeneration after Schwann cell graft to injured spinal cord
  Optimal site for cell transplantation to treat spinal cord injury investigated
  Degenerative cervical spine disease may not progress over time
  Japan tsunami stress may have brought on seizures: study
  Development of prosthetic hands stagnated for twenty years
  Stryker to take charge to end US knee-device probe
  High-level trauma care may limit disability
  Risk of Blood Loss in Childhood Back Surgery Varies with Cause of Spine Deformity
  Researchers Find Epidural Steroid Injections Do Not Benefit Spine Patients
  College Athlete Died of Head Trauma, Father Says


Home | About Us | FAQ | Contact | Advertising Policy | Privacy Policy | Bookmark Site