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Benign prostatic hyperplasia, or BPH for short, is the enlargement of the prostate gland. It is caused by excess growth of cells in the prostate. This condition is not the same as prostate cancer






You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Anticholinergics/Antispasmodics

Anticholinergics/Antispasmodics (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects | Additional Information

Category
  • Anesthesia adjunct - Scopolamine
  • Antiarrhythmic - Atropine; Glycopyrrolate; Hyoscyamine; Scopolamine
  • Anticholinergic - Anisotropine; Atropine; Belladonna; Clidinium; Dicyclomine; Glycopyrrolate; Homatropine; Hyoscyamine; Mepenzolate; Methantheline; Methscopolamine; Pirenzepine; Propantheline; Scopolamine
  • Antidiarrheal - Glycopyrrolate
  • Antidote, to cholinesterase inhibitors - Atropine; Hyoscyamine
  • Antidote, to muscarine - Atropine; Hyoscyamine
  • Antidote, to organophosphate pesticides - Atropine
  • Antidysmenorrheal - Belladonna; Scopolamine
  • Antiemetic - Scopolamine
  • Antispasmodic, gastrointestinal - Dicyclomine; Scopolamine
  • Antispasmodic, urinary tract - Atropine; Scopolamine
  • Antivertigo agent - Belladonna; Scopolamine
  • Cholinergic adjunct, curariform block - Atropine; Glycopyrrolate; Hyoscyamine
Description

The anticholinergics/antispasmodics are a group of medicines that include the natural belladonna alkaloids (atropine, belladonna, hyoscyamine, and scopolamine) and related products.

The anticholinergics/antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Some are used together with antacids or other medicine in the treatment of peptic ulcer. Others are used to prevent nausea, vomiting, and motion sickness.

Anticholinergics/antispasmodics are also used in certain surgical and emergency procedures. In surgery, some are given by injection before anesthesia to help relax you and to decrease secretions, such as saliva. During anesthesia and surgery, atropine, glycopyrrolate, hyoscyamine, and scopolamine are used to help keep the heartbeat normal. Scopolomine is also used to prevent nausea and vomiting after anesthesia and surgery. Atropine is also given by injection to help relax the stomach and intestines for certain types of examinations. Some anticholinergics are also used to treat poisoning caused by medicines such as neostigmine and physostigmine, certain types of mushrooms, and poisoning by “nerve”" gases or organic phosphorous pesticides (for example, demeton [Systox], diazinon, malathion, parathion, and ronnel [Trolene]). Also, anticholinergics can be used for painful menstruation, runny nose, and to prevent urination during sleep.

These medicines may also be used for other conditions as determined by your doctor.

The anticholinergics/antispasmodics are available only with your doctor's prescription in the following dosage forms:

    Oral
  • Anisotropine
    • Tablets (U.S.)
  • Atropine
    • Tablets (U.S.)
    • Soluble tablets (U.S.)
  • Belladonna
    • Tincture (U.S.)
  • Clidinium
    • Capsules (U.S.)
  • Dicyclomine
    • Capsules (U.S. and Canada)
    • Syrup (U.S. and Canada)
    • Tablets (U.S. and Canada)
  • Glycopyrrolate
    • Tablets (U.S. and Canada)
  • Homatropine
    • Tablets (U.S.)
  • Hyoscyamine
    • Extended-release capsules (U.S.)
    • Extended-release tablets (U.S.)
    • Elixir (U.S.)
    • Oral solution (U.S. and Canada)
    • Tablets (U.S. and Canada)
  • Mepenzolate
    • Tablets (U.S.)
  • Methantheline
    • Tablets (U.S.)
  • Methscopolamine
  • Pirenzepine
    • Tablets (Canada)
  • Propantheline
    • Tablets (U.S. and Canada)
  • Scopolamine
    • Tablets (Canada)
    Parenteral
  • Atropine
    • Injection (U.S. and Canada)
  • Dicyclomine
    • Injection (U.S. )
  • Glycopyrrolate
    • Injection (U.S. and Canada)
  • Hyoscyamine
    • Injection (U.S. )
  • Scopolamine
    • Injection (U.S. and Canada)
    Rectal
  • Scopolamine
    • Suppositories (Canada)
    Transdermal
  • Scopolamine
    • Transdermal disk (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Anaspaz 8
  • A-Spas S/L 8
  • Banthine 10
  • Bentyl 5
  • Cantil 9
  • Cystospaz 8
  • Cystospaz-M 8
  • Donnamar 8
  • ED-SPAZ 8
  • Gastrosed 8
  • Homapin 7
  • Levbid 8
  • Levsin 8
  • Levsinex Timecaps 8
  • Levsin/SL 8
  • Pro-Banthine 13
  • Quarzan 4
  • Robinul 6
  • Robinul Forte 6
  • Symax SL 8
  • Transderm-Scop 14

In Canada -

  • Bentylol 5
  • Buscopan 14
  • Formulex 5
  • Gastrozepin 12
  • Levsin 8
  • Pro-Banthine 13
  • Propanthel 13
  • Robinul 6
  • Robinul Forte 6
  • Spasmoban 5
  • Transderm-V 14

Other commonly used names are: dicycloverine , glycopyrronium bromide , hyoscine hydrobromide , hyoscine methobromide , methanthelinium , and octatropine

Note:

For quick reference, the following anticholinergics/antispasmodics are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Anisotropine (an-iss-oh-TROE-peen)†‡
2. Atropine (A-troe-peen)‡§
3. Belladonna (bell-a-DON-a)†‡
4. Clidinium (kli-DI-nee-um)†
5. Dicyclomine (dye-SYE-kloe-meen)‡
6. Glycopyrrolate (glye-koe-PYE-roe-late)‡
7. Homatropine (hoe-MA-troe-peen)†
8. Hyoscyamine (hye-oh-SYE-a-meen)‡
9. Mepenzolate (me-PEN-zoe-late)†
10. Methantheline (meth-AN-tha-leen)†
11. Methscopolamine (meth-skoe-POL-a-meen)*†
12. Pirenzepine (peer-EN-ze-peen)*
13. Propantheline (proe-PAN-the-leen)‡
14. Scopolamine (scoe-POL-a-meen)‡
* Not commercially available in the U.S.
† Not commercially available in Canada
‡ Generic name product may be available in the U.S.
§ Generic name product may be available in Canada

   

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Anticholinergics/Antispasmodics: Before Using



Benign prostatic hyperplasia, or BPH for short, is the enlargement of the prostate gland. It is caused by excess growth of cells in the prostate. This condition is not the same as prostate cancer





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