Antihemophilic Factor (Systemic)
Brand Names : Alphanate, Bioclate, Helixate, Hemofil M, Humate-P, Hyate:C, Koate-HP, Kogenate, Kogenate FS, Helixate FS, Monarc-M, Monoclate-P, Recombinate, AHF, factor VIII
Antihemophilic (an-tee-hee-moe-FIL-ik) factor (AHF)
is a protein produced naturally in the body. It helps the blood form clots
to stop bleeding.
Hemophilia A, also called classical hemophilia, is a condition in which
the body does not make enough AHF. If you do not have enough AHF and you become
injured, your blood will not form clots as it should, and you may bleed into
and damage your muscles and joints. One type of AHF is used to treat another
condition called von Willebrand disease, in which there is a risk of bleeding.
AHF also may be used for other conditions as determined by your doctor.
The AHF that your doctor will give you is obtained naturally from human
or pig blood or artificially by a man-made process.
AHF obtained from human blood has been treated. It is not likely to contain
harmful viruses such as hepatitis B virus; hepatitis C virus (non-A, non-B
hepatitis); or human immunodeficiency virus (HIV), the virus that causes acquired
immunodeficiency syndrome (AIDS). The man-made and pork AHF products do not
contain these viruses.
AHF is available only with your doctor's prescription, in the following
Injection (U.S. and Canada)
Some commonly used brand names are:
In the U.S. -
- Hemofil M
- Kogenate FS
- Helixate FS
In Canada -
- Hemofil M
Generic name product may be available in the U.S. and Canada.
Other commonly used names are AHF
and factor VIII