Thrombolytic Agents (Systemic)
Category- Thrombolytic - Alteplase, Recombinant; Anistreplase; Reteplase,
Recombinant; Streptokinase; Urokinase
DescriptionThrombolytic agents are used to dissolve blood
clots that have formed in certain blood vessels. These medicines are usually
used when a blood clot seriously lessens the flow of blood to certain parts
of the body.
Thrombolytic agents are also used to dissolve blood clots that form in
tubes that are placed into the body. The tubes allow treatments (such as dialysis
or injections into a vein) to be given over a long period of time.
These medicines are to be given only by or under the direct supervision
of a doctor.
These medicines are available in the following dosage forms:
Parenteral
-
Alteplase, Recombinant
-
Injection (U.S. and Canada)
-
Anistreplase
-
Injection (U.S. and Canada)
-
Reteplase, Recombinant
-
Streptokinase
-
Injection (U.S. and Canada)
-
Urokinase
-
Injection (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S. -
- Abbokinase 5
- Abbokinase Open-Cath 5
- Activase 1
- Eminase 2
- Retavase 3
- Streptase 4
In Canada -
- Abbokinase 5
- Abbokinase Open-Cath 5
- Activase rt-PA 1
- Eminase 2
- Streptase 4
Other commonly used names are: Anisoylated plasminogen-streptokinase activator
complex , APSAC , tissue-type plasminogen activator (recombinant) , t-PA , and
rt-PA .
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Note:
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For quick reference, the following thrombolytic agents are
numbered to match the corresponding brand names.
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| This information applies to the following medicines: |
| 1. |
Alteplase, Recombinant (AL-te-plase) |
| 2. |
Anistreplase (a-NISS-tre-place) |
| 3. |
Reteplase,Recombinant (RE-te-plays)† |
| 4. |
Streptokinase (strep-toe-KIN-ace) |
| 5. |
Urokinase (yoor-oh-KIN-ace) |
| † Not commercially available in Canada |
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