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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Colony Stimulating Factors

Colony Stimulating Factors (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects | Additional Information

  • Antineutropenic - Filgrastim; Sargramostim
  • Hematopoietic stimulant - Filgrastim; Sargramostim

Filgrastim and sargramostim are synthetic (man-made) versions of substances naturally produced in your body. These substances, called colony stimulating factors, help the bone marrow to make new white blood cells.

When certain cancer medicines fight your cancer cells, they also affect those white blood cells that fight infection. To help prevent infections when these cancer medicines are used, colony stimulating factors may be given. Colony stimulating factors also may be used to help the bone marrow recover after bone marrow transplantation and stem cell transplantation.

Colony stimulating factors are available only with your doctor's prescription, in the following dosage form:

  • Filgrastim
    • Injection (U.S. and Canada)
  • Sargramostim
    • Injection (U.S.)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Neupogen 1
  • Leukine 2

In Canada -

  • Neupogen 1

Other commonly used names are:

  • Granulocyte colony stimulating factor (G-CSF)
  • Granulocyte-macrophage colony stimulating factor (GM-CSF)


For quick reference, the following colony stimulating factors are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Filgrastim (fil-GRA-stim)
2. Sargramostim (sar-GRAM-oh-stim)†
† Not commercially available in Canada


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Colony Stimulating Factors: Before Using

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