Congenital Lack of Intrinsic Factor

Alternate Names : Congenital Pernicious Anemia

What are the treatments for the disease?

Congenital lack of intrinsic factor is usually treated with injections of vitamin B12 into a muscle. An injection is usually needed once a month for life. Pill forms of vitamin B12 cannot be used because a person without intrinsic factor cannot absorb the vitamin from the intestines.

What are the side effects of the treatments?

Injections can cause soreness at the site of the needle stick.

What happens after treatment for the disease?

A person with congenital lack of intrinsic factor needs lifelong treatment. Most children grow up to be healthy and can lead normal lives with no restrictions. Further treatment may be needed if nervous system damage has occurred.

How is the disease monitored?

Monitoring is not usually needed unless nervous system damage is present. Any new or worsening symptoms should be reported to the healthcare provider.